Name: Chicken Bubble Biscuit Casserole
Prep time: 10 min
Cook time: 35 min
Total time: 45 min
Cuisine: American
Ingredients: 2 cups cooked shredded chicken; 1 can (10.5 oz) cream of chicken soup; 1 cup sour cream; 1/2 cup milk; 1 1/2 cups shredded cheddar cheese; 1/2 teaspoon garlic powder; 1/2 teaspoon onion powder; 1/4 teaspoon salt; 1/4 teaspoon black pepper; 1 can (16 oz) refrigerated biscuit dough

Comfort food doesn’t get much more satisfying than a creamy, cheesy, bubbling casserole fresh out of the oven. Chicken Bubble Biscuit Casserole takes everything you love about homestyle meals and wraps it in a warm, golden-brown biscuit topping that makes every bite irresistible. It’s simple enough for weeknights but hearty enough to serve guests who crave that cozy, made-from-scratch feel.

This dish is a delicious mash-up of creamy chicken filling, gooey cheese, and tender biscuits that puff up perfectly in the oven. With minimal prep and just a handful of ingredients, this casserole is a true lifesaver for busy days or last-minute dinners. It’s comfort food, pure and simple.

Why You’ll Love This Chicken Bubble Biscuit Casserole

This casserole checks all the boxes: easy, quick, filling, and family-approved. The biscuits bake right on top of the creamy chicken mixture, soaking in flavor while becoming perfectly fluffy and golden. It’s a one-dish wonder that doesn’t sacrifice flavor for simplicity.

Whether you’re looking to feed a crowd or stretch a rotisserie chicken into a full meal, this recipe fits the bill. It also makes great leftovers, reheating beautifully the next day for lunch or another dinner.

What Kind of Biscuits Should I Use?

Refrigerated biscuit dough is your best bet for ease and consistency. Buttermilk or homestyle biscuits work great, especially the larger, flaky varieties. Avoid the “grands” style if you want a more even bake, as those can be too large and doughy inside. You can also cut larger biscuits into quarters before baking to help them cook evenly.

Ingredients for the Chicken Bubble Biscuit Casserole

The beauty of this dish is in its simplicity. Each ingredient plays a comforting role, from creamy soup to savory chicken to golden biscuit tops. Here’s what you’ll need:

Cooked chicken – Whether it’s shredded rotisserie chicken or leftover baked chicken, this brings the protein and heartiness.

Refrigerated biscuit dough – These bubble up beautifully as they bake, creating a golden crown over the casserole.

Cream of chicken soup – This adds creaminess and classic casserole flavor.

Sour cream – Brings tang and extra creamy texture to the sauce.

Shredded cheddar cheese – Melts right into the sauce and on top for that gooey goodness.

Milk – Helps loosen the soup and sour cream mixture for the perfect consistency.

Garlic powder and onion powder – These give your sauce a savory boost without extra chopping.

Salt and pepper – Essential for seasoning every bite just right.

How To Make the Chicken Bubble Biscuit Casserole

Step 1: Prep Your Oven

Preheat your oven to 350°F and lightly grease a 9×13 inch baking dish to prevent sticking.

Step 2: Make the Creamy Filling

In a large mixing bowl, combine the cream of chicken soup, sour cream, milk, shredded cheese, garlic powder, onion powder, salt, and pepper. Stir until smooth. Add in your cooked, shredded chicken and mix until fully coated.

Step 3: Add the Biscuits

Cut your refrigerated biscuits into quarters or smaller chunks. Gently fold them into the creamy chicken mixture until they are all coated and evenly distributed.

Step 4: Assemble and Bake

Pour the entire mixture into your greased baking dish, spreading it evenly. Optionally, sprinkle a little extra cheese on top. Bake uncovered for 30-35 minutes, or until the biscuits are puffed and golden, and the casserole is bubbling.

Step 5: Rest and Serve

Let the casserole rest for about 5 minutes before serving. This helps everything set slightly and makes scooping easier.

How to Serve and Store Chicken Bubble Biscuit Casserole

This recipe easily feeds 6 to 8 people, making it perfect for a big family dinner or potluck. Serve it straight from the dish while the biscuits are still warm and fluffy.

Leftovers can be stored in an airtight container in the refrigerator for up to 3 days. To reheat, microwave individual portions or warm the dish in the oven at 300°F until heated through. The biscuits might soften a bit but will still be delicious.

What to Serve With Chicken Bubble Biscuit Casserole?

A Crisp Garden Salad

A fresh salad with vinaigrette adds a bright, crunchy contrast to the creamy casserole.

Steamed Green Beans

Simple and buttery green beans complement the richness without competing.

Roasted Carrots

Slightly sweet and caramelized, they add color and a touch of natural sugar.

Cranberry Sauce

A little tangy and sweet, cranberry sauce adds a festive twist.

Baked Apples

Warm spiced apples on the side echo classic comfort food vibes.

Coleslaw

A creamy or vinegar-based coleslaw cuts the richness of the dish.

Cornbread

If you’re feeding a crowd, serve with a basket of cornbread on the side.

Mashed Potatoes

For ultra comfort, double up on carbs with a scoop of creamy mashed potatoes.

Want More Casserole Ideas?

If you love this hearty chicken casserole, here are some other comforting recipes to add to your list:

Creamy Chicken and Broccoli for a veggie-packed meal.
Easy Brunch Casserole that works for breakfast-for-dinner nights.
Cheesy Baked Ziti for that pasta-meets-casserole craving.
Loaded Cheddar Ranch Rotini Bake when you want extra cheesy goodness.
Chicken Pot Pie Bake with Cheddar Bay Biscuits if you’re into biscuit-topped comfort meals.

Save This Recipe For Later

📌 Save this recipe to your Pinterest dinner board so you can come back to it any time.

And let me know in the comments how yours turned out. Did you use homemade biscuits or refrigerated ones? Add any spices or extras?

I love seeing how everyone puts their own spin on it. Questions are always welcome too – let’s help each other make every meal better.

Explore beautifully curated casseroles and comfort food ideas on Zoe Recipes on Pinterest and find your next dinner hit: Zoe Recipes on Pinterest

Conclusion

Chicken Bubble Biscuit Casserole is the kind of meal that brings people together. With its easy prep, cozy flavor, and that irresistible biscuit topping, it’s a recipe you’ll want to keep in rotation. It’s perfect for chilly evenings, busy weeknights, or anytime you need a little taste of home.